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Pharmaceutical Estriol Strongest Anabolic Steroid Estrogen Hormone Cas 50 27 1

Pharmaceutical Estriol Strongest Anabolic Steroid Estrogen Hormone Cas 50 27 1

    • Pharmaceutical Estriol Strongest Anabolic Steroid Estrogen Hormone Cas 50 27 1
    • Pharmaceutical Estriol Strongest Anabolic Steroid Estrogen Hormone Cas 50 27 1
  • Pharmaceutical Estriol Strongest Anabolic Steroid Estrogen Hormone Cas 50 27 1

    Product Details:

    Brand Name: RedBird

    Payment & Shipping Terms:

    Minimum Order Quantity: 10Grams
    Price: Negotiated
    Packaging Details: Foil Bag
    Delivery Time: 3-7days after received payment
    Payment Terms: T/T, Western Union, MoneyGram
    Supply Ability: 5000Kg Per Month
    Contact Now
    Detailed Product Description
    Product Name: Estriol Cas: 50-27-1
    Appearance: White Powder Purity: 99%min
    Formula: C18H24O3 Usage: Female Health
    High Light:

    healthy anabolic steroids

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    Pharmaceutical Estriol Strongest Anabolic Steroid Estrogen Hormone Cas 50 27 1

     

     

    Name: Estriol
    CAS No.: 50-27-1
    Formula: C18H24O3
    Molecular Weight: 288.39
    EINECS: 200-022-2
    Purity: 99%
    Appearance: White crystalline powder
    Application: Pharmaceutical active ingredient

     

    Estriol Description:
    Estriol is a natural estrogen which is associated with pregnancy. In pregnant women, estriol is produced in the fetus by the fetal liver and in the placenta. Levels of estriol in the blood and urine can be used to determine whether or not a woman is pregnant, and to monitor the progress of the pregnancy. Abnormal estriol levels can indicate that there is a problem with the developing fetus which could bear closer monitoring or additional testing. The quad screen routinely recommended to pregnant women includes a check on estriol levels.

     

    Estriol levels are typically highest in women of childbearing age, and they increase during pregnancy. Otherwise, estriol levels in women and men are fairly similar, unless estriol is being taken as a supplement. This hormone is sometimes used to manage the symptoms of menopause, and it has been used in the treatment of some other conditions as well. Levels of estriol in women taking supplements can be very high.

     

    Application:

    Hormonal contraception:
    A chemical derivative of estradiol, ethinyl estradiol with maximum dosage 200 μg, is a major component of hormonal contraceptive devices. Combined forms of hormonal contraception contain ethinyl estradiol and a progestin, which both contribute to the inhibition of GnRH, LH, and FSH, which accounts for the ability of these birth control methods to prevent ovulation and thus prevent pregnancy. Other types of hormonal birth control contain only progestins and no ethinyl estradiol.


    COA:




    TEST ITEMS

    SPECIFICATION

    RESULTS

    Description

    : White or Almost White Crystalline Powder

    white powder

    Identification

    : A.B.

    Positive

    Assay

    : 97.0~102.0%

    99.3%

    Specific Rotation

    : +101°~+105°

    +102.6°

    Loss On Drying

    : 1.0%max

    0.27%

    Melting Point

    : 153~157°C

    153.0~155.0°C

    Organic Volatile Impurities

    : meets the requirement.

    Conforms

    Related Substances

    : meets the requirement.

    Conforms

    Residual Solvents

    : meets the requirement.

    Conforms

    Particle Size

    : 100% ≤ 20 microns

    Conforms
    Conclusion
    The specification conform with USP30 standard

     

     

    Abstract

     

    Estriol belongs to natural hormone and is the metabolite of estradiol in vivo , anti estrogen steroids . It is mainly presented in the urine . Estrogen has a relative small activity with the oral activity being 6 times as high as estrone but being weaker than estradiol with non-carcinogenic effects . After its administration , the in vivo estradiol levels did not change . Estriol has selective action on the vaginal and cervical canal but has no effect on the uterus and endometrium entity .

     

    Estriol,Animal experiments have shown that estriol has a stronger effect on vaginal epithelial keratosis than estradiol , thus being able to promote vaginal epithelial hyperplasia , superficial cells keratosis , mucosal angiogenesis and vaginal epithelial wound healing , but having a weak effect on the weight gain of mouse uterus At the same time , estriol can enhance the function of cervix cell , causing the cervix muscle fiber hyperplasia and increasing the cervical elasticity and softness .

     

    In addition , estriol has feedback inhibition on the hypothalamus and pituitary but does not inhibit ovulation while only having significant impact on the corpus luteum and therefore can be used as the auxiliary drug in the medium-term labor induction and artificial abortion and for the treatment of various kinds of menopathy . Estriol also has significant effect on the hematopoietic system and can reduce vascular permeability and fragility. Therefore , it can be used for the treatment of various kinds of hemorrhage . It also has effect of rapidly increasing the peripheral leukocytes and generally begins to take effect at 1 to 3 days after treatment but with a shorter duration of action and is effective in treatment the leukopenia induced by radiotherapy and chemotherapy

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