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Metformin Pharmaceutical Anabolic Steroids Hcl / Hydrochloride Cas 1115-70-4

Metformin Pharmaceutical Anabolic Steroids Hcl / Hydrochloride Cas 1115-70-4

    • Metformin Pharmaceutical Anabolic Steroids Hcl / Hydrochloride Cas 1115-70-4
    • Metformin Pharmaceutical Anabolic Steroids Hcl / Hydrochloride Cas 1115-70-4
  • Metformin Pharmaceutical Anabolic Steroids Hcl / Hydrochloride Cas 1115-70-4

    Product Details:

    Brand Name: RedBird

    Payment & Shipping Terms:

    Minimum Order Quantity: 100Grams
    Price: Negotiated
    Packaging Details: Foil Bag
    Delivery Time: 3-7days after received payment
    Payment Terms: T/T, Western Union, MoneyGram
    Supply Ability: 5000Kg Per Month
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    Detailed Product Description
    Product Name: Metformin HCl Assay: 99%
    Appearance: White Powder Cas: 1115-70-4
    MF: C4H12ClN5 Grade: Pharmaceutical Grade
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    Metformin Pharmaceutical Anabolic Steroids Hcl / Hydrochloride Cas 1115-70-4

     

     

    Basic Info.:

    Metformin HCL
    Metformin Hydrochloride; 3-(diaminomethylidene)-1,1-dimethylguanidine hydrochloride
    CAS NO.:1115-70-4
    EINECS: 214-230-6
    Formula:C4H12ClN5
    Molecular Weight:165.6246
    Melting Point:220 ~ 225 ºC.
    Appearance: white crystalline powder; odorless. soluble in water, dissolved in methanol, slightly soluble in ethanol, insoluble in chloroform or ether.
    Absorption coefficient of this product, accurately weighed, dissolved in water and diluted quantitatively per 1ml solution containing 5μg. According to the spectrophotometric determination of absorbance at 233nm wavelength, the absorption coefficient of 778 ~ 818

    Description:

    Metformin hydrochloride is the first choice of first-line hypoglycemic agents, this class of drugs do not stimulate pancreatic β-cells, almost no effect on normal people, and type 2 diabetes significantly hypoglycemic effect. It does not affect insulin secretion, mainly through the promotion of peripheral tissue uptake of glucose, gluconeogenesis inhibition, reduce hepatic glycogen output, delayed glucose absorption in the intestine, thereby reducing the role of blood sugar.

    Applications:

    1. Metformin, is an antidiabetic medication which is taken by mouth. It is the first-line drug of choice for the treatment of type 2 diabetes, in particular, in overweight and obese people and those with normal kidney function.Its use in gestational diabetes has
    been limited by safety concerns. It is also used in the treatment of polycystic ovary syndrome, and has been investigated for other diseases where insulin resistance may be an important factor. Metformin works by suppressing glucose production by the liver
    .
    2. Limited evidence suggests metformin may prevent the cardiovascular and possibly the cancer complications of diabetes.It
    helps reduce LDL cholesterol and triglyceride levels and is not associated with weight gain; in some people, it promotes weight loss.Metformin is one of only two oral antidiabetics in the World Health Organization Model List of Essential Medicines (the other being glibenclamide)

    3. Metformin is primarily used for type 2 diabetes, but is increasingly being used in polycystic ovary syndrome,non-alcoholic fatty liver disease (NAFLD)and premature puberty,three other diseases that feature insulin resistance; these indications are still considered experimental. The benefit of metformin in
    NAFLD has not been extensively studied and may be only temporary;although some randomized controlled trials have found significant improvement with its use, the evidence is still insufficient.

    COA:

    Item Specifications (USP) Specifications (AJI)
    Description White crystals or crystalline powder White crystals or crystalline powder
    Identification Infrared absorption spectrum Infrared absorption spectrum
    Specific rotation
    [a]D20°
    +26.3 °- +27.7° +26.9 °- +27.9°
    State of solution
    /Transmittance
    --- ≥ 98.0%
    Chloride (Cl) ≤ 0.05% ≤ 0.020%
    Ammonium (NH4) --- ≤ 0.02%
    Sulfate (SO4) ≤ 0.03% ≤ 0.020%
    Iron (Fe) ≤ 0.003% ≤ 10PPm
    Heavy metals (Pb) ≤ 0.0015% ≤ 10PPm
    Arsenic (As2O3) --- ≤ 1PPm
    Other amino acids --- Chromatographically not detectable
    Loss on drying ≤ 0.5% ≤ 0.5%
    Residue on ignition
    (sulfated)
    ≤ 0.3% ≤ 0.10%
    Assay 98.5-101.5% 99.0 - 101.0%
    PH --- 10.5-12.0
    Organic volatile impurities Meets the requirements ---

     

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