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Dxm Dextromethorphan Hydrobromide Raw Materials For Pharmaceutical Industry

Dxm Dextromethorphan Hydrobromide Raw Materials For Pharmaceutical Industry

Dxm Dextromethorphan Hydrobromide Raw Materials For Pharmaceutical Industry

Product Details:

Brand Name: RedBird

Payment & Shipping Terms:

Minimum Order Quantity: 10Grams
Price: Negotiated
Packaging Details: Foil Bag
Delivery Time: 3-7days after received payment
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000KG Per Month
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Detailed Product Description
Product Name: Dextromethorphan Hydrobromide Synonyms: DXM
Molecular Formula: C18H26BrNO Appearance: White Crystalline Powder
Usage: Antitussive Drugs Cas: 125-69-9
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Dxm Dextromethorphan Hydrobromide Raw Materials For Pharmaceutical Industry

 

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Product Name: Dextromethorphan Hydrobromide

Synonyms:Delsym;Sisaal;Dextro;ROMILAR;medicon;tusilan;Tussade;antussan;metrorat;Dormetan;;Romilar;Tussade;

CAS No.: 125-69-9

Einecs No:204-750-1

Molecular Formula: C18H26BrNO

Molecular Weight: 352.31

Purity: 99.0%

Appearance: white crystalline powder

Standard: Enterprise Standard

Packing: 25KG/Drum or as per your requirements

Application: medical use

Chemical Properties and Usage:

Chemical Properties White Solid
Usage An antitussive drug. Orally active synthetic morphine analog. Analgesic (narcotic). Racemethorphan and levomethorpham are controlled substances (opiates).
Usage Antitussive;Opioid ligand
Biological Activity Non-competitive, low affinity NMDA receptor antagonist. Antitussive, anticonvulsive and neuroprotective agent.

Dextromethorphan hydrobromide monohydrate

1. Dextromethorphan hydrobromide is used to treat a dry (nonproductive) cough caused by colds, flu or inhaled irritants.

2. The primary use of dextromethorphan hydrobromide is as an antitussive, or cough suppressant. This is one of the most popular ingredients in over-the-counter cold and cough medications.

3. Dextromethorphan hydrobromide may be added to other preparations to help treat pain and a variety of other disturbances as well.

Dextromethorphan hydrobromide COA:

TEST SPECIFICATION
Apperance Practically white crystal or crystalline powder
Identification A. FT-IR The sample spectrum correspond to that of the reference standard
  B. UV Not more than 3.0% difference of RS(on anhydrous basis)
  C. Bromide Test Yellow white precipitate formed
Specific rotation A 1.8w/v in water:Not more than 1.0%difference of RS
At 325nm and 25ºC(on anhydrous basis)
Specific rotation B 2.0%w/v in 0.1M HCL: +28ºCto +30ºC at 589nm and
20ºC(on anhydrous basis)
Clarity of solution 5.0%w/v in alcohol:Clear and colorless
PH 5.2-6.5(1 in 100 water solution)
Acidity or Alkalinity Not more than 0.4ml of 0.01M HCLconsumed
Water(by KF Titration) 4.0%-5.5%
Relates substances
(by HPLC;ph;Eur)
a)For each of impurities A,B,C,D not more than 0.5%
  b)Among impurities A,B,C,D not more than one greater than 0.25%
  C)For each of unspecified impurities,not more than0.10%
  d)Total impurities not more than 1.0%
Residue on Ignition Not more than 1.0%
N,N-Dimethylaniline Not more than 0.001%
Phenolic compounds No blue-green color develops
Assay A (by HPLC) 98.0%~102.0%(on anhydrous basis)
Assay B(by titration) 99.0%~101.0%(on anhydrous basis)
Residual solvents Methanol≤3000ppm
Acetone≤5000ppm
Storage Preserve in tight containers;protected from light

 

Dextromethorphan Applications:

DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist. The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist.. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.

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