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Cas 62568-57-4 Peptides Muscle Growth Hormone Dsip Lyophilized Powder

Cas 62568-57-4 Peptides Muscle Growth Hormone Dsip Lyophilized Powder

    • Cas 62568-57-4 Peptides Muscle Growth Hormone Dsip Lyophilized Powder
    • Cas 62568-57-4 Peptides Muscle Growth Hormone Dsip Lyophilized Powder
  • Cas 62568-57-4 Peptides Muscle Growth Hormone Dsip Lyophilized Powder

    Product Details:

    Brand Name: RedBird

    Payment & Shipping Terms:

    Minimum Order Quantity: 10Vials
    Price: Negotiated
    Packaging Details: Disguise Package
    Delivery Time: 3-7days after received payment
    Payment Terms: T/T, Western Union, MoneyGram
    Supply Ability: 5000Kg Per Month
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    Detailed Product Description
    Product Name: DSIP Cas: 62568-57-4
    Purity: 99% Usage: Muscle Mass
    MF: C35H48N10O15 Specification: 2mg/vial
    High Light:

    human growth peptides

    ,

    steroid based hormones

    Cas 62568-57-4 Peptides Muscle Growth Hormone Dsip Lyophilized Powder

     

    Detail:

     

    DSIP
    Product Details:
    Alias: Delta Sleep Inducing Peptide
    CAS: 62568-57-4
    Sequence: TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU
    MF: C35H48N10O15
    MW: 848.813620
    Purity: 99%
    Specification: 2mg/vial
    Appearance: White Lyophilized Powder
    Place of Origin: China
    Standard: USP
    Certification: SGS
    Method of Analysis: HPLC
    Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C.

     

    Description:

    Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.

    Delta sleep-inducing peptide was first discovered in 1974 by the Swiss Schoenenberger-Monnier group who isolated it from the cerebral venous blood of rabbits in an induced state of sleep. It was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits, but studies on the subject have been contradictory.

    DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:
    N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C

    It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.

    In the brain its action may be mediated by NMDA receptors. In another study Delta sleep-inducing peptide stimulated Acetyltransferase activity through α1 receptors in rats.It is unknown where DSIP is synthesized.

     

     

    Application:

    Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.

    Many roles for DSIP have been suggested following research carried out using peptide analogues with a greater molecular stability and through measuring DSIP-like immunological (DSIP-LI) response by injecting DSIP antiserum and antibodies.

     

    Background And Objective:


    Delta sleep-inducing peptide (DSIP) is an endogenous peptide that crosses the blood-brain barrier, named after its association with natural sleep and enhanced electroencephalogram (EEG) delta rhythm. The objective of this study was to determine whether DSIP could be used as an adjunct to volatile anaesthesia in humans, our hypothesis being that DSIP is a natural hypnotic that would increase anaesthetic depth. The aims were to assess depth of anaesthesia using bispectral index (BIS), the EEG and heart rate variability (HRV), and to determine whether DSIP altered the symmetry of EEG between the left and right cerebral hemispheres.

     

    Results:


    DSIP significantly increased heart rate, decreased HRV and, paradoxically, significantly reduced delta rhythm along with reducing burst suppression and increasing BIS at 25 nmol kg(-1) during isoflurane anaesthesia. DSIP also significantly altered bilateral symmetry of EEG.

     

    Conclusion:


    DSIP probably reduced parasympathetic tone and decreased (lightened) the depth of anaesthesia measured using BIS

    Cas 62568-57-4 Peptides Muscle Growth Hormone Dsip Lyophilized Powder

     

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