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10238-21-8 Weight Loss Steroids Glybenclamide For Antidiabetic Glibenclamide

10238-21-8 Weight Loss Steroids Glybenclamide For Antidiabetic Glibenclamide

    • 10238-21-8 Weight Loss Steroids Glybenclamide For Antidiabetic Glibenclamide
    • 10238-21-8 Weight Loss Steroids Glybenclamide For Antidiabetic Glibenclamide
  • 10238-21-8 Weight Loss Steroids Glybenclamide For Antidiabetic Glibenclamide

    Product Details:

    Brand Name: RedBird

    Payment & Shipping Terms:

    Minimum Order Quantity: 100Grams
    Price: Negotiated
    Packaging Details: Foil Bag
    Delivery Time: 3-7days after received payment
    Payment Terms: T/T, Western Union, MoneyGram
    Supply Ability: 5000Kg Per Month
    Contact Now
    Detailed Product Description
    Product Name: Glibenclamide Alias: Glybenclamide
    Appearance: White Powder Assay: 99%
    Usage: Antidiabetic MF: C23H28ClN3O5S
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    10238-21-8 Weight Loss Steroids Glybenclamide For Antidiabetic Glibenclamide

     

     

    product Name:

    5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide
    Synonyms: LABOTEST-BB LT00244861;GLYBENCLAMIDE;GLYBENZCYCLAMIDE;GLYBURIDE;GIBENCLAMIDE;
    GLIBENCLAMIDE;5-CHLORO-N-[4-(CYCLOHEXYLUREIDOSULFONYL)PHENETHYL]-2-METHOXYBENZAMIDE;5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]-SULFONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE
    CAS: 10238-21-8
    MF: C23H28ClN3O5S
    MW: 494
    EINECS: 233-570-6
    Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Organics;Amino Acids &
    Derivatis;Isotope Labeled Compounds;API's;Potassium channel;Ion Channels;Isotope Labelled Compounds;API;GLYNASE;Diabetes Research
    Mol File: 10238-21-8.mol
    Chemical Properties White Crystalline Powder
    Usage antihyperglycemic
    Usage Glyburide is a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic.

    Glibenclamide Application


    1. Hypoglycemic drugs,for the treatment of mild,non insulin dependent diabetes mellitus
    2. Glibenclamide and glibenclamide,glibenclamide,which belongs to the second generation oral sulfonylurea drugs,with the mechanism of toluene sulfonyl Ding Niao,its hypoglycemic effect was the strongest sulfonylurea,intensity for tolbutamide 200~250 times.Be selective effect on pancreatic beta cells,promote the secretion of insulin,can enhance the hypoglycemic effect of exogenous insulin,insulin receptor after strengthening effect.
    3. Glibenclamide is one of the drugs currently used to treat type 2 diabetes,the most often used,because the utility function is fast and strong,so after the application has obvious effect,can effectively control blood sugar,high blood sugar,is applicable to other sulfonylurea hypoglycemic effect not beautiful person.

     

    Hypoglycemic Agents Glibenclamide belongs to the second generation oral sulfonylurea drugs with the mechanism of action being similar as tolbutamide and the hypoglycemic effect being strongest among sulfonylurea drugs. Its intensity of action is about 200 to 250 times of that of Tolbutamide. It can selectively act on the pancreatic β-cells, promote secretion; can enhance the hypoglycemic effect of exogeg rate of 90% to 95% and half-life of 4 to 8 hours. It is mainly consumed by the liver metabolism with six metabolites. Two of them are knownous and strengthen the post-receptor effect of . It has fast oral absorption with high protein binding rate. It begins to take effect after 30 minutes with the effect being strongest at 1.5 hours and the duration of 16 to 24 hours. It has a distribution volume of 0.1L/kg, plasma protein bindinn as hydroxylated compounds with no hypoglycemic effect and is mainly excreted from the urine and a small amount is excreted by the stool. It is clinically mainly used for the treatment of mild to moderate non- dependent diabetes mellitus.

     

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